Scientific Programme

PRE-Conference Workshop on Cancer Screening

Cancer is a debilitating disease with a high morbidity and mortality. Some cancers can be identified prior to symptoms by screening tests for early intervention and prevention. The most common cancers in women are breast and cervical carcinomas, both have established screening tests.

It is well established that, “prevention is better than cure”. In this Pre Conference workshop Clinical, Pathological, Genetic and Molecular screening tests for cancer will be dealt with. Identifying, the most suitable screening test for high risk individuals to plan early intervention.

This work shop includes following sessions:

• Clinical screening for cervical cancer by Colposcopy
• Radiological screening for breast cancer
• Pedigree analysis to identify Genetic/Hereditary Breast Cancer Syndromes
• Pathological testing - cytology of cervical smears by Bethseda System
• Molecular testing – HPV- DNA testing and typing for cervical cancer
• BRCA1 and 2 gene mutation interpretation based on sequencing

Advisors

1. Dr.Vasundara Kamineni
2. Dr.Q.Annie Hasan

Hands On Faculty

1. Dr Hari Priya - OBG
2. Dr Annapurna - Radiology
3. Dr . Krishkanth - Pathology
4. Dr Shobha - Genetics
5. Ms. Subhadra Poornima - Genetics
6. Ms Swarna - Genetics
7. Ms Gayatri - Genetics
8. Mr Karthik - Genetics

Support Team

1. Ms. Keerthi - Genetics
2. Ms. Aruna Priya - Genetics
3. Ms. Swarna Kumari - Genetics

Biochemical Screening For New Born and Sick Babies.

The defect in a single gene causes lack of enzyme, membrane transporter or other relevant protein. Ultimately a particular metabolic pathway gets disrupted. This blockage results in an accumulation of a metabolite or a lack of a metabolite post-blockage. Serious congenital disorders like inborn errors of metabolism leads to disability and death of infants.Most of these disorders have safe and effective management and if treated early can prevent significant mortality and morbidity. By the time the symptoms are manifested it is often too late and causes severe physical and mental disability in what could have been a completely normal child. Hence it is imperative in diagnosing these disorders at the earliest. In the developed countries all the newborn babies are screened for these conditions through a newborn screening programme (NBS).The assay of metabolites as disease biomarkers using tandem mass spectrometry for multiple IEM’s has been so successful that it has been extended to population screening in many parts of the world. Dried blood spots using the heel prick technique are used since it is easy and a robust sample collection method for population screening. In Biochemistry labs situated in the medical colleges in India, it may not be viable economically and ethically to screen for a complete range of disorders. But a screening programme would be possible for a biochemically well identified disorder, which is having known incidence especially in our population, and for which an effective treatment will be available.

The objectives of the workshopare to create awareness about the following:

• To initiate the newborn screening program to detect IEM so as to reduce the mortality and morbidity of newborns.
• To understand the cost effectiveness of IEM detection

Hands on training will include:

• General metabolic screening tests
• Thin layer chromatography on amino acids , organic acids and sugars
• Tests for mucopolysaccharodosis.

Resource Faculty

1. Dr. Pragna Rao
2. Mr. Prince Jacob
3. Mr Y. S. Phaneendra